SAMe, Fight depression and get pain relief

SAMe (Adenosylmethionine), an amino acid methionine derivative that contains sulfur Is formed in the body when methionine combines with Adenosine triphosphate (APT), the primary source of cellular energy. Adenosylmethionine plays an important role in the manufacturing of cartilage and has proven to be very effective in conditions such as soft tissue and joint disease.

Adenosylmethionine was first studied in Italy in the fifties as a treatment for depression but during the study it was observed that Osteoathritis patients were benefitting as well. So now you have a product that can treat depression and relieve certain forms of joint and tissue pain also. More recent studies have found this compound to be as effective as non-steroidal anti-inflammatory drugs.

This compound is the 3rd most concentrated chemical in the liver and may be effective in treating diseases and disorders such as cirrhosis, jaundice, and hepatitis. It is also instrumental in the normalization of live enzyme levels and decreasing itching associated with liver disease. As pointed out in another page on this site, it may also be effective in treating fibromyalgia. Those who use alcohol beyond moderation should consider the use of adenosylmethionine as it protects the stomach from over consumption.

SAMe has been available by prescription in Europe for a number of years but it only hit the shelves in the U.S. somewhere in the mid to late nineties as an over-the-counter supplement. These now over-the-counter supplements once sold for as a few hundred dollars per month if prescribed by a physician. Today, a 30 supply is substantially less money.If melatonin can be referred to as a night-time sleep hormone, then this product can be referred to as the day-time alertness hormone because of the significant role it plays in the production of energy of life molecule.




Fibromyalgia Clinical studies have showed that adenosylmethionine produces impressive benefits in patients suffering from fibromyalgia. During treatment of injections, subjects demonstrated a measurable reduction in the number of trigger points and painful areas and at the same time moods were also improved. More extensive evaluations revealed that patient’s condition and symptoms improve in muscle fatigue, muscle weakness, morning stiffness and an overall improvement in general mobility.

SAMe is not found in abundance in any food source, so if your body requires more of this substance than it can produce, then the alternative is supplements. This product is available in capsules, coated pills and can be administered using injections. Recommended daily doses should be on the box or container.

Side effects Are not that common but they can occur. These will include anxiety, diarrhea, gas, hyperactive muscles movement and insomnia.

SAM-e 400 mg.-400 mg.-30-Tablets

Fibromyalgia, A related subject, click here

Fibromyalgia Symptoms, A related subject, click here

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